Coronavirus
Structural Task Force
Coronavirus SARS-CoV-2 geschlossene, wissenschaftliche Illustration von Thomas Splettstoesser, www.scistyle.comCoronavirus SARS-CoV-2 offene, wissenschaftliche Illustration von Thomas Splettstoesser, www.scistyle.com

SARS-CoV-2 - The Coronavirus

This is the coronavirus SARS-CoV-2.

The coronavirus consists mainly of large protein molecules, which make up the virus hull and the protruding spikes, which allow it to infect a host cell.

Inside of SARS-CoV-2 is the RNA - blueprints for more molecules which, once a human cell is infected, hijack the cell to produce new copies of the virus.

If we understand these molecules, we cannot only learn how the virus works, but may also find a cure. Antibodies (produced from vaccines) and small molecules (drugs) both bind to these protein macromolecules like keys to a lock and can deactivate them.

The Coronavirus Structural Task Force evaluates the molecular structures from Coronavirus, improves them by pushing the structural biology methods to their limit and puts these structures into context for drug developers and other scientists.

This transmission electron microscope image shows SARS-CoV-2, the virus that causes COVID-19, isolated from a patient. Image captured and colorized at NIAID's Rocky Mountain Laboratories (RML) in Hamilton, Montana. Credit: NIH-NIAID.

Interview:
"What is coronavirus and what are you doing?"

More about the Coronavirus Structural Taskforce in the media

Latest Posts

December 24, 2020
SARS-CoV-2 Entry Animation from Iwasa Group – a little Christmas Present to the Scientific Community

See how the virus binds to a host cell and manages to insert its RNA on a molecular level! Merry Christmas from the Iwasa Lab and the Coronavirus Structural Task Force!

Read More
December 23, 2020
The new mutation of SARS-CoV-2

The new strain of Coronavirus - what do we know?

Read More
December 22, 2020
How do we know that Viruses exist?

If you want to know how exactly science found out about the existence of viruses, this post is for you!

Read More
December 10, 2020
How reliable is the Pfizer-BioNTech claim that their vaccine is 90 percent effective?

On Nov 9th, 2020 Pfizer issued a press release stating their conclusion that the COVID-19 vaccine they developed with BioNTech appeared to be 90% effective. While their test contained over 43,000 volunteers they had only detected 94 cases of COVID-19. How confident can you be with only 94 cases? I decided to explore this matter […]

Read More
November 9, 2020
What does the Pfizer press release really mean?

A press release came out today from Pfizer and Binotech with a very exciting announcement, but what does it say? Andrea shares her insights.

Read More
November 9, 2020
The healing power of crystals

Join us at Wednesday the 11th for this not quite serious talk about some real science behind modern therapies!

Read More
September 1, 2020
Exoribonuclease: Making the most when mistakes are made

Exoribonuclease is a domain of nsp14 responsible for chopping out nucleotides incorrectly added by RdRp. This enzyme allows the large 29.9 kb genome of SARS-CoV-2 and remains a worthwhile target for drugs to fight this virus.

Read More
August 20, 2020
Rage Against the Machine with Remdesivir

RNA Polymerase is central to virus replication, and Remdesivir stops it. How? Learn here!

Read More
July 31, 2020
What does the Coronavirus really look like?

You cannot see the virus. Until now!

Read More
July 30, 2020
How to make your own 3D printed coronavirus model

The instructions and files below will allow you to create your own model of the virus! All you need is some spare time and a 3D printer.

Read More
Coronavirus Structural Taskforce
Top