Coronavirus
Structural Task Force

SARS-CoV-2—The coronavirus

The coronavirus SARS-CoV-2 consists of molecules making up the virus hull, the protruding spikes (which allow it to infect a host cell) and the RNA genome inside. This RNA is a collection of blueprints that cause the infected host cell to produce new copies of the virus. If you would like to know how this works in more detail, you can find an animated viral life cycle here, along with explanations.
Coronavirus SARS-CoV-2 geschlossene, wissenschaftliche Illustration von Thomas Splettstoesser, www.scistyle.com
If we understand these molecules, we cannot only learn how the virus works but may also find a cure. Antibodies (e.g. produced through vaccination) and small molecules (drugs) both bind to these protein macromolecules like keys to a lock and can deactivate them.

The Coronavirus Structural Task Force evaluates the protein structures from coronavirus, improves them by pushing the structural biology methods to their limit, and puts these structures into context for drug developers and other scientists.

TL;DR? Watch this video:
Elektronenmikroskopische Aufnahme von SARS-CoV-2, dem Erreger von COVID-19. Diese Viren wurden aus einem Patienten isoliert.
This transmission electron microscope image shows SARS-CoV-2, the virus that causes COVID-19, isolated from a patient. Image captured and colorized at NIAID's Rocky Mountain Laboratories (RML) in Hamilton, Montana. Credit: NIH-NIAID.
Learn more about the Coronavirus Structural Task Force in the media!

Latest Posts

June 17, 2021
Where are the drugs?

Why are vaccines developed so quickly and treatments so slowly? In March 2020, the WHO declared COVID-19 a pandemic. Since then, 14 vaccines have entered the global market[1], and the number of immunized people grows every day. Even though vaccine development has never been this fast in history and will save many lives worldwide, people […]

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June 10, 2021
Sizes of Viruses, Droplets, Aerosols, and the Construction of Masks

This article looks deep into the internal structure of masks, and discusses different types of masks and how they work. Interesting!

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May 28, 2021
Opinion: Can the Strategy of the Ongoing COVID-19 Vaccination End the Pandemic Fast Enough?

COVID-19 vaccines were developed in record time and vaccination exercise is of course ongoing in most countries. Everyone is anxious to see the pandemic come to an end for things to return to normal. As of 23rd April 2021, more than 966 million doses have been administered worldwide [1], however, we have to remember that […]

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May 20, 2021
Babelian SARS-CoV-2 confusion

There is a secret code that virologists use to talk about the new coronavirus. This code is made up of synonymous words and abbreviations for each of the 28 proteins which facilitate the viral life cycle. In this article, we will shed some light on this mythical language. First of all, SARS-CoV-2 has three classes […]

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April 29, 2021
Ironic: Using viruses to fight coronavirus

In addition to mRNA vaccines, another type of vaccine is employed against COVID-19: Vector vaccines—like the one from AstraZeneca—contain a mostly functioning virus. But how do they work exactly? What are their strengths and weaknesses? And finally, are they safe? The novel mRNA vaccines against SARS-CoV-2 have caused some controversy, and many concerns have been […]

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April 1, 2021
Vaccination Safety Management

Introduction: Vaccination is a great means of achieving public protection against diseases. The main goal of any vaccine manufacturer is to produce a vaccine that will be safe and effective in preventing the target disease. Before any vaccine is rolled out for mass vaccination or campaign, it must have met the required rigorous scientific and […]

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February 22, 2021
Opinion: Press release about "Coronavirus Origin Study" by Prof. Wiesendanger and Hamburg University

“The coronavirus has led to a worldwide crisis for over a year. In a new study, nanoscientist Prof. Dr. Roland Wiesendanger illuminates the origins of the virus. His findings conclude there are a number of quality sources indicating a laboratory accident at the Wuhan Institute of Virology as the cause of the current pandemic.” This […]

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February 22, 2021
How SARS-CoV-2 (Coronavirus) mRNA-based Vaccines Work

In this blogpost Joshua explains how we are immune with Covid-19 vaccine.

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December 24, 2020
SARS-CoV-2 Entry Animation from Iwasa Group – a little Christmas Present to the Scientific Community

See how the virus binds to a host cell and manages to insert its RNA on a molecular level! Merry Christmas from the Iwasa Lab and the Coronavirus Structural Task Force!

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December 23, 2020
The new mutation of SARS-CoV-2

The new strain of Coronavirus - what do we know?

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Coronavirus Structural Taskforce
Universität Hamburg
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