Structural Task Force

SARS-CoV-2 - The Coronavirus

The coronavirus SARS-CoV-2 consists of molecules, which make up the virus hull, the protruding spikes, which allow it to infect a host cell and the RNA genome inside - blueprints for more protein molecules which, once a human cell is infected, hijack the host cell to produce new copies of the virus. If you would like to know how this works in more detail, you can find an animated viral life cycle here along with explanations.
Coronavirus SARS-CoV-2 geschlossene, wissenschaftliche Illustration von Thomas Splettstoesser,
If we understand these molecules, we cannot only learn how the virus works, but may also find a cure. Antibodies (produced from vaccines) and small molecules (drugs) both bind to these protein macromolecules like keys to a lock and can deactivate them.

The Coronavirus Structural Task Force evaluates the protein structures from Coronavirus, improves them by pushing the structural biology methods to their limit and puts these structures into context for drug developers and other scientists.

TL;DR? Watch this video:
Elektronenmikroskopische Aufnahme von SARS-CoV-2, dem Erreger von COVID-19. Diese Viren wurden aus einem Patienten isoliert.
This transmission electron microscope image shows SARS-CoV-2, the virus that causes COVID-19, isolated from a patient. Image captured and colorized at NIAID's Rocky Mountain Laboratories (RML) in Hamilton, Montana. Credit: NIH-NIAID.
More about the Coronavirus Structural Taskforce in the media

Latest Posts

April 1, 2021
Vaccination Safety Management

Introduction: Vaccination is a great means of achieving public protection against diseases. The main goal of any vaccine manufacturer is to produce a vaccine that will be safe and effective in preventing the target disease. Before any vaccine is rolled out for mass vaccination or campaign, it must have met the required rigorous scientific and […]

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February 22, 2021
Opinion: Press release about "Coronavirus Origin Study" by Prof. Wiesendanger and Hamburg University

“The coronavirus has led to a worldwide crisis for over a year. In a new study, nanoscientist Prof. Dr. Roland Wiesendanger illuminates the origins of the virus. His findings conclude there are a number of quality sources indicating a laboratory accident at the Wuhan Institute of Virology as the cause of the current pandemic.” This […]

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February 22, 2021
How SARS-CoV-2 (Coronavirus) mRNA-based Vaccines Work

In this blogpost Joshua explains how we are immune with Covid-19 vaccine.

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December 24, 2020
SARS-CoV-2 Entry Animation from Iwasa Group – a little Christmas Present to the Scientific Community

See how the virus binds to a host cell and manages to insert its RNA on a molecular level! Merry Christmas from the Iwasa Lab and the Coronavirus Structural Task Force!

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December 23, 2020
The new mutation of SARS-CoV-2

The new strain of Coronavirus - what do we know?

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December 22, 2020
How do we know that Viruses exist?

If you want to know how exactly science found out about the existence of viruses, this post is for you!

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December 10, 2020
How reliable is the Pfizer-BioNTech claim that their vaccine is 90 percent effective?

On Nov 9th, 2020 Pfizer issued a press release stating their conclusion that the COVID-19 vaccine they developed with BioNTech appeared to be 90% effective. While their test contained over 43,000 volunteers they had only detected 94 cases of COVID-19. How confident can you be with only 94 cases? I decided to explore this matter […]

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November 9, 2020
What does the Pfizer press release really mean?

A press release came out today from Pfizer and Binotech with a very exciting announcement, but what does it say? Andrea shares her insights.

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September 1, 2020
Exoribonuclease: Making the most when mistakes are made

Exoribonuclease is a domain of nsp14 responsible for chopping out nucleotides incorrectly added by RdRp. This enzyme allows the large 29.9 kb genome of SARS-CoV-2 and remains a worthwhile target for drugs to fight this virus.

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August 20, 2020
Rage Against the Machine with Remdesivir

RNA Polymerase is central to virus replication, and Remdesivir stops it. How? Learn here!

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Coronavirus Structural Taskforce
Universität Hamburg
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