Coronavirus
Structural Task Force
Coronavirus SARS-CoV-2 geschlossene, wissenschaftliche Illustration von Thomas Splettstoesser, www.scistyle.comCoronavirus SARS-CoV-2 offene, wissenschaftliche Illustration von Thomas Splettstoesser, www.scistyle.com

SARS-CoV-2 - The Coronavirus

This is the coronavirus SARS-CoV-2.

The coronavirus consists mainly of large protein molecules, which make up the virus hull and the protruding spikes, which allow it to infect a host cell.

Inside of SARS-CoV-2 is the RNA - blueprints for more molecules which, once a human cell is infected, hijack the cell to produce new copies of the virus.

If we understand these molecules, we cannot only learn how the virus works, but may also find a cure. Antibodies (produced from vaccines) and small molecules (drugs) both bind to these protein macromolecules like keys to a lock and can deactivate them.

The Coronavirus Structural Task Force evaluates the molecular structures from Coronavirus, improves them by pushing the structural biology methods to their limit and puts these structures into context for drug developers and other scientists.

This transmission electron microscope image shows SARS-CoV-2, the virus that causes COVID-19, isolated from a patient. Image captured and colorized at NIAID's Rocky Mountain Laboratories (RML) in Hamilton, Montana. Credit: NIH-NIAID.

Interview:
"What is coronavirus and what are you doing?"

More about the Coronavirus Structural Taskforce in the media

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April 7, 2020
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