Dale Tronrud has both solved protein crystal structures and developed methods and software for the optimization of macromolecular models against X-ray data and known chemical structural information.
He has had a long-standing interest in enzyme:inhibitor complexes and photosynthetic proteins, focusing on the Fenna-Matthews-Olson protein. In addition, he has also been involved in the validation and repair of many PDB models.
Getting the chemistry right has been critical to all these projects. And this is exactly what Dale also does in the task force. He also occasionally teaches the other members some the secrets of crystallographic refinement.