David Briggs is a Principal Laboratory Research Scientist in the Signalling and Structural Biology lab at the Francis Crick Institute in London, UK. A crystallographer by training, his work focuses on the biophysical and structural characterisation of human extracellular proteins involved in the synapse, which have important ramifications in both psychiatric and neurodegenerative disorders. He is also involved in structure-based drug design projects targeting receptor tyrosine kinases that are involved in various metastatic disorders and has a track record of working on difficult, highly modified targets. He is one of the macromolecular crystallography reps on the Diamond Light Source User Committee.