Structural Task Force

Kristopher Nolte

Biochemistry B.Sc. Student

Kristopher joined the Thorn Lab as part of his bachelor thesis.
In this thesis he will refine aspects of the diagnostic tool for graphical X-Ray data analysis (AUSPEX) with the help of machine learning.

But since the corona crisis halted all our lives he contributes to the task force by using his knowledge of bioinformatics and programming to collect, organize, update all Coronavirus-relevant data from the protein data bank (PDB).

Apart from this he will investigate the proteins of SARS-CoV-2 through bioinformatic tools and will share his results on inside corona.

Posts of Kristopher Nolte

SARS-CoV-2 nsp3 Papain-like-protease (PDB-ID:6W9C)

Untangling Nsp3 of SARS-CoV-2

Kristopher Nolte
April 22, 2020
The world holds its breath as the novel Coronavirus continues to spread across the world, bringing our lives to a halt. We have gathered a lot of knowledge about the virus but there are still many gaps to fill. The non-structural-protein 3 (nsp3) represents one of these gaps in our knowledge. As the largest protein […]

Untangling nsp3 - Papain-like Protease

Kristopher Nolte
June 28, 2020
An important drug target In the first part of this series we compared the protein nsp3 from SARS-CoV and SARS-CoV-2 by sequence. Now we delve deeper into the differences between these two proteins and follow through by analyzing the structure of one domain of nsp3 in particular: papain-like protease. This domain is a very relevant […]
Computer rendered image of corona virus by Thomas Splettstoesser (left), and finished 3D print by Thorn Lab (right). Picture on the left by Thomas Splettstößer (

How to make your own 3D printed coronavirus model

Kristopher Nolte
July 30, 2020
The instructions and files below will allow you to create your own model of the virus! All you need is some spare time and a 3D printer. In addition, those without access to a 3D printer can still use the STL files to request printing from external services and then follow the instructions on painting […]
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