See how the virus binds to a host cell and manages to insert its RNA on a molecular level! Merry Christmas from the Iwasa Lab and the Coronavirus Structural Task Force!
See how the virus binds to a host cell and manages to insert its RNA on a molecular level! Merry Christmas from the Iwasa Lab and the Coronavirus Structural Task Force!
If you want to know how exactly science found out about the existence of viruses, this post is for you!
On Nov 9th, 2020 Pfizer issued a press release stating their conclusion that the COVID-19 vaccine they developed with BioNTech appeared to be 90% effective. While their test contained over 43,000 volunteers they had only detected 94 cases of COVID-19. How confident can you be with only 94 cases? I decided to explore this matter […]
Methyltransferases manage to fool the host cell into giving viral RNA VIP treatment. For details, read this blog post by Cameron Fyfe and Lea von Soosten!
A press release came out today from Pfizer and Binotech with a very exciting announcement, but what does it say? Andrea shares her insights.
Join us at Wednesday the 11th for this not quite serious talk about some real science behind modern therapies!
The genome of the novel SARS-CoV-2 codes for an ORF1a/ ORF1ab (open reading frame) polyprotein containing sixteen non-structural proteins (NSP) and four structural proteins. The genome also has multiple ORFs coding for accessory proteins through a frame shift. These accessory proteins are not necessary for viral replication but might play a key role in pathogenesis […]
Exoribonuclease is a domain of nsp14 responsible for chopping out nucleotides incorrectly added by RdRp. This enzyme allows the large 29.9 kb genome of SARS-CoV-2 and remains a worthwhile target for drugs to fight this virus.
RNA Polymerase is central to virus replication, and Remdesivir stops it. How? Learn here!